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Bernhard K Keppler Selected Research

Benzazepines

12/2011Conjugation of organoruthenium(II) 3-(1H-benzimidazol-2-yl)pyrazolo[3,4-b]pyridines and indolo[3,2-d]benzazepines to recombinant human serum albumin: a strategy to enhance cytotoxicity in cancer cells.
8/2010Organometallic indolo[3,2-c]quinolines versus indolo[3,2-d]benzazepines: synthesis, structural and spectroscopic characterization, and biological efficacy.

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Bernhard K Keppler Research Topics

Disease

141Neoplasms (Cancer)
06/2022 - 07/2002
30Carcinoma (Carcinomatosis)
03/2021 - 01/2005
10Colonic Neoplasms (Colon Cancer)
10/2019 - 01/2004
8Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
03/2020 - 08/2008
6Colorectal Neoplasms (Colorectal Cancer)
10/2021 - 01/2004
6Hypoxia (Hypoxemia)
03/2021 - 04/2016
4Neoplasm Metastasis (Metastasis)
12/2021 - 08/2015
4Ovarian Neoplasms (Ovarian Cancer)
08/2019 - 01/2004
3Teratocarcinoma
03/2020 - 12/2015
3Hematologic Diseases (Blood Diseases)
01/2020 - 01/2016
3Osteosarcoma (Osteogenic Sarcoma)
11/2018 - 10/2008
3Adenocarcinoma
01/2012 - 11/2007
2Leukemia
12/2021 - 03/2021
2Melanoma (Melanoma, Malignant)
01/2020 - 10/2009
2Breast Neoplasms (Breast Cancer)
01/2020 - 01/2016
2Malaria
10/2019 - 12/2009
2Lung Neoplasms (Lung Cancer)
06/2017 - 10/2014
2Leukemia L1210
01/2017 - 01/2014
2Necrosis
03/2015 - 10/2014
2Hepatocellular Carcinoma (Hepatoma)
10/2013 - 10/2008
1Hypersensitivity (Allergy)
12/2021
1Ganglion Cysts (Ganglion)
01/2021
1Sarcoma (Soft Tissue Sarcoma)
12/2020

Drug/Important Bio-Agent (IBA)

29Pharmaceutical PreparationsIBA
12/2021 - 06/2003
29PlatinumIBA
10/2021 - 06/2003
28RutheniumIBA
01/2022 - 06/2005
27LigandsIBA
03/2021 - 06/2003
26Cisplatin (Platino)FDA LinkGeneric
11/2018 - 01/2005
20MetalsIBA
01/2022 - 01/2004
18Oxaliplatin (Eloxatin)FDA LinkGeneric
10/2021 - 01/2004
13ProdrugsIBA
10/2021 - 07/2015
12Biological ProductsIBA
01/2022 - 12/2009
123-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine)IBA
11/2021 - 01/2010
11GalliumIBA
12/2017 - 07/2002
10OsmiumIBA
01/2022 - 08/2008
9ThiosemicarbazonesIBA
11/2021 - 06/2012
8KP 1339IBA
08/2021 - 06/2010
8DNA (Deoxyribonucleic Acid)IBA
11/2020 - 12/2006
8IndazolesIBA
01/2019 - 06/2005
8indazolium trans- (tetrachlorobis(1H- indazole)ruthenate (III))IBA
07/2014 - 08/2005
7Coordination ComplexesIBA
08/2019 - 06/2003
6Tyrosine Kinase InhibitorsIBA
03/2021 - 11/2016
6IronIBA
12/2020 - 01/2004
6Proteins (Proteins, Gene)FDA Link
12/2019 - 05/2008
64-cymene (p-cymene)IBA
10/2018 - 05/2009
5Antineoplastic Agents (Antineoplastics)IBA
12/2021 - 11/2006
4SodiumIBA
01/2019 - 06/2015
4diphenyl (biphenyl)IBA
03/2013 - 10/2008
3RhodiumIBA
01/2022 - 08/2018
3AlbuminsIBA
10/2021 - 03/2017
3SolutionsIBA
10/2021 - 01/2014
3CopperIBA
11/2020 - 09/2012
3Peptides (Polypeptides)IBA
06/2017 - 07/2013
3CationsIBA
11/2009 - 01/2004
3Ruthenium CompoundsIBA
08/2008 - 06/2007
2IridiumIBA
01/2022 - 01/2020
2EstroneFDA Link
10/2021 - 01/2021
2Oxygen (Dioxygen)IBA
03/2021 - 11/2016
2CobaltIBA
03/2021 - 12/2020
2Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
03/2021 - 01/2019
2ponatinibIBA
03/2021 - 11/2018
2maleimideIBA
01/2021 - 03/2017
2Glutathione (Reduced Glutathione)IBA
11/2020 - 02/2013
2Biotin (Vitamin H)FDA Link
01/2019 - 03/2015
2Carboplatin (JM8)FDA LinkGeneric
11/2018 - 03/2015
2Arsenic Trioxide (Trisenox)FDA Link
02/2017 - 01/2004
2NKP-1339IBA
01/2017 - 01/2016
2IntegrinsIBA
01/2017 - 10/2014
2Blood Proteins (Serum Proteins)IBA
01/2016 - 12/2009
2VanadiumIBA
11/2015 - 06/2015
2CymenesIBA
03/2013 - 11/2009
2Transferrin (beta 2 Transferrin)IBA
02/2013 - 11/2006
2CarbohydratesIBA
01/2013 - 01/2008
2Human Serum AlbuminFDA LinkGeneric
12/2011 - 07/2007
2BenzazepinesIBA
12/2011 - 08/2010
2BromidesIBA
10/2009 - 12/2008
2tris(8-quinolinolato)gallium (III)IBA
11/2006 - 01/2004
2Ribonucleotide Reductases (Ribonucleotide Reductase)IBA
01/2004 - 01/2004
2Transferrin Receptors (Transferrin Receptor)IBA
01/2004 - 01/2004
2gallium nitrateFDA Link
01/2004 - 01/2004
1carbeneIBA
06/2022
1Diphosphonates (Bisphosphonates)IBA
12/2021
1ApatitesIBA
12/2021
1ClathrinIBA
10/2021
1CaveolinsIBA
10/2021
1salicylaldehyde thiosemicarbazoneIBA
10/2021
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
01/2021
1Endoplasmic Reticulum Chaperone BiPIBA
01/2021
1Ribosomal Proteins (Ribosomal Protein)IBA
01/2021
1ElementsIBA
01/2021
1polyanionsIBA
03/2020
1trans-sodium crocetinate (crocetin)IBA
01/2020
112-Hydroxy-5,8,10,14-eicosatetraenoic AcidIBA
01/2020
1CrizotinibIBA
01/2020
1EicosanoidsIBA
01/2020

Therapy/Procedure

19Therapeutics
12/2021 - 01/2004
10Drug Therapy (Chemotherapy)
10/2021 - 01/2004
3Laser Therapy (Surgery, Laser)
11/2020 - 08/2015
2Transplantation
11/2018 - 08/2012
2Aftercare (After-Treatment)
01/2017 - 04/2015